The Exposure Biology Informatics Core (EBIC), directed by Dr. Jason Moore, is a CEET funded service core that is dedicated to provide bioinformatics support to CEET members in the areas of bioinformatics application development, multi-omics data management and integration, NGS data analysis, and machine learning. The main role of EBIC is assist the CEET investigator community with bioinformatics needs that will support a pilot-project or analysis of preliminary data for a grant application. It can also assist investigators in the analysis of discrete data sets for manuscript publication. Project intensive bioinformatics support can be provided only if the investigator includes bioinformatics support in pending or awarded grants as a fee-for-service. EBIC is pleased to consult on an individual basis to scope project need and support.
We offer accessible and user-friendly artificial intelligence software (PennAI) developed at Penn for computational analysis of complex biomedical data.
Our staff are familiar with cutting-edge bioinformatics analysis methods and techniques including the implementation and use of software pipelines for the analysis of large-scale genomic data from next-generation sequencing. We make heavy use of the open-source R package for data science.
We maintain an Oracle-based relational database that can be adapted to virtually any data storage, management, and retrieval needs. This includes a web interface for data entry and management.
We are familiar with many popular machine learning algorithms for the identification of complex patterns in large-scale data. These include cluster analysis, neural networks, random forests, support vector machines, and several novel methods such as the Tree-Based Pipeline Optimization Tool (TPOT) developed locally by Penn bioinformatics investigators for automated machine learning.
We can plan and implement complex software packages for specific projects. These can include standalone software with user-friendly graphic user interfaces or software implemented through the web.
We have advanced capability for data visualization and interactive visual analysis. This includes priority access to a state-of-the-art immersive visualization facility.
We can assist with all aspects of web programming and web page design and implementation.